Methylation Pathology Profile![Testing Methylation through pathology testing]()
The methylation cycle is a biochemical pathway that is involved in a number of processes, such as:
- Detoxification
- Supporting DNA (turning genes on and off)
- Energy production
- Reducing inflammation
- Neurotransmitter production
- Amino acid (particularly homocysteine) metabolism
- Immune function
Impaired methylation capacity has been linked to various autoimmune and neurological conditions, including (but not limited to):
- Autism spectrum disorder, ADD/ADHD and birth defects (methylation support has been associated with rapid return of speech, and improvement in behaviour in ADD and ADHD)
- Anxiety and depression
- Chronic fatigue syndrome
- Cognitive decline/dementia
- Seizure disorders
- Multiple sclerosis
- Lupus
- Cancer
The markers assessed in the Methylation Profile include:
- S-adenosyl methionine (SAMe)
- S-adenosyl homocysteine (SAH)
- SAMe:SAH ratio
- Folinic acid
- 5-methyl tetrahydrofolate (5MTHF)
- Tetrahydrofolate (THF)
We also recommend testing for any MTHFR gene mutations.
Interested in understanding your methylation status? Book your free naturopathic assessment consultation